Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 9/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594983 | 0.79 | EPHX1 (0.38) | EPHX1 | |
| SCHEMBL2899251 | 0.79 | GRM2 (0.40) | — | |
| SCHEMBL10392022 | 0.79 | GRM2 (0.40) | — | |
| SCHEMBL12662227 | 0.78 | MAPT (0.41) | TDP1 | |
| Hydrochloric Acid SCHEMBL3129049 | 0.77 | ARG1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL3484004 | 0.76 | MAPT (0.41) | TDP1 | |
| SCHEMBL2901770 | 0.72 | ARG1 (0.45) | TDP1 | |
| SCHEMBL27667817 | 0.71 | KMT2A (0.36) | HTTTDP1 | |
| Hydrochloric Acid SCHEMBL1632919 | 0.71 | ARG1 (0.44) | — | |
| SCHEMBL20103922 | 0.70 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |