Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 15/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.54 |
| ▸ | HTR3B | O95264 | 5/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436991 | 0.83 | HTR3A (0.74) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7440165 | 0.81 | HTR3A (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7432150 | 0.77 | RECQL (0.69) | — | |
| SCHEMBL4187655 | 0.76 | MEN1 (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL8802904 | 0.76 | FEN1 (0.54) | — | |
| SCHEMBL8802662 | 0.73 | FEN1 (0.54) | — | |
| SCHEMBL9045112 | 0.73 | FEN1 (0.51) | — | |
| SCHEMBL7430312 | 0.72 | HTR3A (0.58) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL4192599 | 0.72 | PDE4A (0.49) | — | |
| SCHEMBL4187649 | 0.71 | CNR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458636-B1 | Antiemetic and migraine suppressing heterocyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1995-07-12 | — | — | EP | disclosed |