Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 14/20 | 0.72 |
| ▸ | HTR3E | A5X5Y0 | 9/20 | 0.72 |
| ▸ | HTR3B | O95264 | 9/20 | 0.72 |
| ▸ | HTR3D | Q70Z44 | 9/20 | 0.72 |
| ▸ | HTR3C | Q8WXA8 | 9/20 | 0.72 |
| ▸ | CNR2 | P34972 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435062 | 0.85 | HTR3A (0.70) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7433210 | 0.81 | HTR3A (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1522890 | 0.80 | KDM4E (0.69) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7301955 | 0.80 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7301949 | 0.80 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7302698 | 0.76 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7302702 | 0.76 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439911 | 0.76 | HTR3A (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2088519 | 0.71 | KDM4E (0.53) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7433224 | 0.71 | HTR3A (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458636-B1 | Antiemetic and migraine suppressing heterocyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1995-07-12 | — | — | EP | disclosed |