Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 4/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438477 | 0.88 | TLR2 (0.51) | MDM2TLR2CASP3KMT2AMDM4 | |
| SCHEMBL30759363 | 0.87 | MDM2 (0.52) | MDM2TLR2MDM4TP53 | |
| SCHEMBL27407606 | 0.85 | KMT2A (0.49) | TLR2CASP3KMT2A | |
| SCHEMBL13950982 | 0.84 | CASP3 (0.47) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL24084089 | 0.83 | MDM4 (0.51) | MDM2TLR2CASP3KMT2AMDM4 | |
| SCHEMBL16310460 | 0.81 | TLR2 (0.51) | MDM2TLR2KMT2AMDM4TP53 | |
| SCHEMBL24899366 | 0.80 | MDM4 (0.52) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL17193154 | 0.80 | TLR2 (0.50) | TLR2CASP3KMT2A | |
| SCHEMBL19134428 | 0.80 | CASP3 (0.50) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL31149057 | 0.80 | CASP3 (0.50) | MDM2CASP3KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |