Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652619 | 0.89 | CASP3 (0.52) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL13815185 | 0.89 | CASP3 (0.52) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL7433227 | 0.88 | MDM2 (0.45) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL27407606 | 0.88 | KMT2A (0.49) | TLR2CASP3KMT2A | |
| SCHEMBL21837734 | 0.87 | TLR2 (0.51) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL21837732 | 0.87 | TLR2 (0.51) | TLR2CASP3KMT2AMDM4TP53 | |
| SCHEMBL7420121 | 0.85 | TLR2 (0.62) | TLR2CASP3MDM4TP53MDM2 | |
| SCHEMBL29382791 | 0.85 | TLR2 (0.62) | TLR2CASP3MDM4TP53MDM2 | |
| SCHEMBL30645689 | 0.85 | TLR2 (0.62) | TLR2CASP3MDM4TP53MDM2 | |
| SCHEMBL1044856 | 0.85 | TLR2 (0.62) | TLR2CASP3MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |