Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CASR | P41180 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440850 | 0.90 | MAPT (0.60) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7434975 | 0.88 | RAB9A (0.63) | ALDH1A1HPGDRAB9AHSD17B10MEN1 | |
| SCHEMBL391430 | 0.88 | FOLH1 (0.60) | ALDH1A1HPGDRAB9AFOLH1HSD17B10 | |
| SCHEMBL7434454 | 0.86 | FOLH1 (0.59) | ALDH1A1HPGDRAB9AFOLH1HSD17B10 | |
| SCHEMBL7435298 | 0.86 | RAB9A (0.49) | ALDH1A1RAB9ASMN1; SMN2HSD17B10MME | |
| SCHEMBL7396819 | 0.85 | PARP1 (0.52) | ALDH1A1HPGDFOLH1HSD17B10MEN1 | |
| SCHEMBL9587139 | 0.85 | RAB9A (0.48) | ALDH1A1HPGDRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7430630 | 0.85 | RAB9A (0.48) | ALDH1A1RAB9AFOLH1SMN1; SMN2CASR | |
| SCHEMBL9724805 | 0.84 | RAB9A (0.65) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL7434449 | 0.84 | MME (0.50) | ALDH1A1HPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |