Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435298 | 0.87 | RAB9A (0.49) | RAB9ALMNAMAPTSMN1; SMN2MME | |
| SCHEMBL7440850 | 0.86 | MAPT (0.60) | RAB9AMAPTSMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL7438277 | 0.86 | CYP1A2 (0.47) | RAB9ALMNAMAPTCHRM1SMN1; SMN2 | |
| SCHEMBL7434975 | 0.85 | RAB9A (0.63) | RAB9ALMNAMAPTMMEALDH1A1 | |
| SCHEMBL7433322 | 0.85 | ALDH1A1 (0.58) | RAB9ALMNASMN1; SMN2MMEFOLH1 | |
| SCHEMBL7425411 | 0.85 | KMT2A (0.52) | RAB9ALMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7435418 | 0.82 | NPSR1 (0.50) | RAB9AMAPTSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL7434594 | 0.81 | RAB9A (0.47) | RAB9ALMNAMAPTSMN1; SMN2MME | |
| Hydrochloric Acid SCHEMBL7438272 | 0.80 | RAB9A (0.44) | RAB9AMAPTSMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL391430 | 0.80 | FOLH1 (0.60) | RAB9AMAPTMMEFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |