Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430649 | 0.91 | SELL (0.56) | SELLSELPSELEMEN1KMT2A | |
| SCHEMBL7442252 | 0.87 | SELP (0.47) | SELLSELPSELEMAPK1MEN1 | |
| SCHEMBL7430609 | 0.86 | NPC1 (0.46) | SELLSELPSELEMEN1KMT2A | |
| SCHEMBL7433940 | 0.84 | LTB4R (0.62) | MEN1KMT2AMAPTLTB4RPOLB | |
| SCHEMBL7433695 | 0.84 | SELL (0.48) | SELLSELPSELEMAPK1MEN1 | |
| SCHEMBL7435487 | 0.82 | HDAC3 (0.49) | MAPTCYP1A2CYP2C9POLBALDH1A1 | |
| SCHEMBL7437982 | 0.82 | POLB (0.44) | SELPSELEMAPK1POLBALDH1A1 | |
| SCHEMBL7432797 | 0.82 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTCYP2C19CYP1A2 | |
| SCHEMBL7439374 | 0.81 | KMT2A (0.44) | MAPK1MEN1KMT2AMAPTTP53 | |
| SCHEMBL7439282 | 0.80 | KMT2A (0.53) | MEN1KMT2AMAPTCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |