Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425854 | 0.84 | POLB (0.48) | POLBTDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL7435457 | 0.83 | SELP (0.56) | POLBTDP1NPC1RAB9AKDM4E | |
| SCHEMBL7430649 | 0.82 | SELL (0.56) | NPC1RAB9AALDH1A1LMNASELP | |
| SCHEMBL7429346 | 0.82 | SELL (0.45) | POLBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7439282 | 0.80 | KMT2A (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL7433330 | 0.79 | SELP (0.43) | POLBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7431963 | 0.77 | KDM4E (0.54) | POLBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7433961 | 0.76 | ABCC1 (0.47) | NPC1RAB9AKDM4EALDH1A1AKR1C3 | |
| SCHEMBL7442252 | 0.76 | SELP (0.47) | KDM4EHDAC1AKR1C3AKR1C2LMNA | |
| SCHEMBL7435487 | 0.75 | HDAC3 (0.49) | POLBTDP1ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |