Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426875 | 0.90 | KDM4C (0.52) | PKMALOX15GAAMAPTKDM4E | |
| SCHEMBL7428063 | 0.86 | MAPT (0.44) | KMT2AGAAMAPTMEN1KDM4E | |
| SCHEMBL7426816 | 0.84 | ALDH1A1 (0.47) | KMT2AGAAMAPTMEN1KDM4E | |
| SCHEMBL1993952 | 0.83 | GAA (0.66) | KMT2APKMALOX15GAAMAPT | |
| SCHEMBL7435750 | 0.82 | KMT2A (0.47) | KMT2APKMALOX15GAAMAPT | |
| SCHEMBL7430294 | 0.81 | GAA (0.46) | ALOX15GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL13593266 | 0.81 | KMT2A (0.61) | KMT2APKMMEN1PTPN12GPR35 | |
| SCHEMBL7439101 | 0.80 | CA12 (0.52) | GAAMAPTALDH1A1HTTPOLB | |
| SCHEMBL7436440 | 0.80 | SMN1; SMN2 (0.56) | KMT2AGAAMAPTMEN1ALDH1A1 | |
| SCHEMBL7434461 | 0.79 | SMN1; SMN2 (0.55) | KMT2AGAAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |