Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.76 |
| ▸ | PDE4A | P27815 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444440 | 0.88 | MEN1 (0.80) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL29832594 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Dextofisopam SCHEMBL29376877 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Dextofisopam SCHEMBL236796 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Levotofisopam SCHEMBL5431173 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL4585183 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL8086894 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Dextofisopam SCHEMBL8086913 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| Tofisopam SCHEMBL43522 | 0.87 | KMT2A (1.00) | KMT2AMEN1CHRM1PDE4APDE4D | |
| SCHEMBL7434144 | 0.84 | KMT2A (0.86) | KMT2AMEN1CHRM1PDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |