Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073663 | 0.89 | PTPRA (0.30) | PTPRA | |
| SCHEMBL9555107 | 0.85 | PPARG (0.39) | KMT2ALDHACPB2 | |
| SCHEMBL9555112 | 0.85 | PPARG (0.39) | KMT2ALDHACPB2 | |
| SCHEMBL1312464 | 0.85 | PTPRA (0.50) | PTPRACYP3A4SLC7A5 | |
| SCHEMBL1312465 | 0.85 | PTPRA (0.50) | PTPRACYP3A4SLC7A5 | |
| SCHEMBL3839517 | 0.83 | PTPRA (0.31) | PTPRACYP3A4SLC7A5 | |
| Histidine SCHEMBL388563 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5KMT2A | |
| SCHEMBL3159235 | 0.83 | APAF1 (0.40) | PTPRACYP3A4SLC7A5CPB2 | |
| SCHEMBL3670921 | 0.83 | APAF1 (0.40) | PTPRACYP3A4SLC7A5CPB2 | |
| SCHEMBL3156583 | 0.83 | APAF1 (0.40) | PTPRACYP3A4SLC7A5CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278161-A | Racemic mixtures | HOFFMANN-LA ROCHE INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0464572-A2 | Aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-08 | — | — | EP | disclosed |