Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248853 | 1.00 | PIM1 (0.48) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14334925 | 0.90 | PIM1 (0.59) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7543421 | 0.89 | KDM4E (0.47) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23537530 | 0.82 | ALDH1A1 (0.47) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL30023090 | 0.79 | ALDH1A1 (0.47) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23537551 | 0.79 | ALDH1A1 (0.47) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL10323706 | 0.77 | PIM1 (0.47) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL31485752 | 0.77 | CYP3A4 (0.59) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL10322251 | 0.77 | PIM1 (0.53) | PIM1PIM3ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL10749276 | 0.76 | MAOA (0.55) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021183980-A1 | SUBSTITUTED PYRIMIDINES AND TRIAZINES AS HERBICIDES | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| US-4939144-A | PSYCHOLOGICAL DISORDERS; ANXIOLYTIC AND ANTIEMETIC AGENTS | GLAXO GROUP LIMITED (GB) | 1990-07-03 | — | — | US | disclosed |
| EP-0317088-A1 | Ketone derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |