Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440859 | 0.99 | ALDH1A1 (0.51) | KMT2AALDH1A1HPGDMAPTGAA | |
| SCHEMBL7432199 | 0.90 | ALDH1A1 (0.56) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL7432434 | 0.85 | MAPT (0.48) | KMT2AALDH1A1HPGDMAPTGAA | |
| SCHEMBL7438991 | 0.84 | MAPT (0.49) | KMT2AALDH1A1HPGDMAPTGAA | |
| SCHEMBL7432040 | 0.80 | KDM4E (0.54) | KMT2AALDH1A1HPGDMAPTGAA | |
| SCHEMBL7438709 | 0.80 | MME (0.54) | KMT2AALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL7434266 | 0.79 | MME (0.57) | KMT2AALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9456711 | 0.79 | MEN1 (0.54) | KMT2AALDH1A1HPGDMAPTGAA | |
| SCHEMBL7433690 | 0.77 | MME (0.51) | KMT2AALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL19084607 | 0.76 | KDM1A (0.66) | KMT2AALDH1A1HPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |