Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440859 | 0.91 | ALDH1A1 (0.51) | ALDH1A1CYP1A2CYP3A4KMT2AKCNQ2 | |
| SCHEMBL7433764 | 0.90 | KMT2A (0.50) | ALDH1A1POLBTSHRKMT2AKCNQ2 | |
| SCHEMBL7438709 | 0.78 | MME (0.54) | ALDH1A1KMT2AFOLH1HPGDMEN1 | |
| SCHEMBL7435482 | 0.78 | KMT2A (0.56) | ALDH1A1POLBTSHRNPSR1CYP1A2 | |
| SCHEMBL9456711 | 0.77 | MEN1 (0.54) | ALDH1A1KMT2AFOLH1HPGDGAA | |
| SCHEMBL7434266 | 0.77 | MME (0.57) | ALDH1A1KMT2ALMNAFOLH1HPGD | |
| SCHEMBL19084698 | 0.77 | KDM1A (0.67) | ALDH1A1POLBTSHRNPSR1CYP1A2 | |
| SCHEMBL7438991 | 0.77 | MAPT (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL7432434 | 0.76 | MAPT (0.48) | ALDH1A1POLBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7433690 | 0.75 | MME (0.51) | ALDH1A1KMT2AFOLH1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |