Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433085 | 1.00 | ADORA1 (0.67) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL7433081 | 1.00 | ADORA1 (0.67) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL7433279 | 0.90 | ADORA1 (0.54) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL9562387 | 0.88 | ADORA2B (0.74) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL9562389 | 0.88 | ADORA2B (0.74) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL7432088 | 0.85 | ADORA1 (0.67) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL7432084 | 0.85 | ADORA1 (0.67) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL9562437 | 0.83 | ADORA2B (0.56) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL9562434 | 0.83 | ADORA2B (0.56) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL14080833 | 0.83 | ADORA1 (0.64) | ADORA1ADORA2AADORA2BADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415456-B1 | Xanthine compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5525607-A | DIURETICS, BRONCHODILATORS, RENAL PROTECTING AGENTS | KYOWA HAKKO KOGYO CO., LTD (JP) | 1996-06-11 | — | — | US | disclosed |