Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562434 | 1.00 | ADORA2B (0.56) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL9562387 | 0.87 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL9562389 | 0.87 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL9402220 | 0.87 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL9562589 | 0.86 | ADORA1 (0.57) | ADORA2BADORA2AADORA1 | |
| SCHEMBL9562586 | 0.86 | ADORA1 (0.57) | ADORA2BADORA2AADORA1 | |
| SCHEMBL7433085 | 0.83 | ADORA1 (0.67) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL7433081 | 0.83 | ADORA1 (0.67) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL7433803 | 0.83 | ADORA1 (0.67) | ADORA2BADORA2AADORA1ADORA3MEN1 | |
| SCHEMBL9402188 | 0.79 | ADORA2A (0.73) | ADORA2BADORA2AADORA1ADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556778-A2 | Xanthine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |