Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433838 | 1.00 | KDM4E (0.45) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL2295759 | 0.89 | KMT2A (0.49) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL7301131 | 0.89 | KMT2A (0.49) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL5709588 | 0.89 | KMT2A (0.49) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL11981992 | 0.88 | REN (0.48) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL13840602 | 0.88 | REN (0.48) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL421814 | 0.87 | REN (0.48) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL13839332 | 0.87 | REN (0.48) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL22546510 | 0.86 | KMT2A (0.46) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL6664333 | 0.84 | KMT2A (0.55) | KDM4EKMT2AALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |