Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009694 | 0.69 | KDM4E (0.44) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL27880869 | 0.69 | KDM4E (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL10431336 | 0.66 | HPGD (0.54) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL31347868 | 0.65 | MEN1 (0.61) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL11718417 | 0.65 | MEN1 (0.61) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL316802 | 0.64 | KCNMA1 (0.46) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL25131979 | 0.62 | KDM4E (0.48) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL1008405 | 0.62 | MAPT (0.65) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14511319 | 0.62 | HTT (0.62) | KDM4EHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9797513 | 0.62 | KDM4E (0.67) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329070-B1 | Cardiotonic alkanoyl and aroyl oxazolones | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0329070-A1 | Cardiotonic alkanoyl and aroyl oxazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-23 | — | — | EP | disclosed |