Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009473 | 0.76 | NPC1 (0.54) | SMN1; SMN2HIF1AHPGDALDH1A1HSD17B10 | |
| SCHEMBL27465925 | 0.74 | — | — | |
| SCHEMBL27880869 | 0.71 | KDM4E (0.52) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL8012213 | 0.69 | KMT2A (0.49) | KDM4EHPGDALDH1A1MAPTNPC1 | |
| SCHEMBL7433887 | 0.69 | KDM4E (0.41) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL27487992 | 0.69 | — | — | |
| SCHEMBL10431336 | 0.69 | HPGD (0.54) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL31347868 | 0.67 | MEN1 (0.61) | KDM4ESMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL11718417 | 0.67 | MEN1 (0.61) | KDM4ESMN1; SMN2GAAHPGDALDH1A1 | |
| Salicylic Acid SCHEMBL1932767 | 0.65 | ALDH1A1 (0.95) | KDM4ESMN1; SMN2GAAMPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057315-A | INHIBIT BACTERIAL SIGNAL TRANSDUCTION IN MAMMALS | WARNER-LAMBERTT COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0942912-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998025932-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |