Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713028 | 0.86 | TSHR (0.63) | MEN1KMT2ACYP1A2HDAC6GAA | |
| SCHEMBL1491848 | 0.84 | MEN1 (0.68) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL1396833 | 0.84 | MEN1 (0.68) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL18652056 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL14495131 | 0.83 | SLC22A6 (0.57) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL16360980 | 0.83 | MEN1 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL1119567 | 0.83 | MEN1 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Apocynin SCHEMBL28350129 | 0.83 | MEN1 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL23829906 | 0.81 | HTT (0.67) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL9174843 | 0.81 | MEN1 (0.64) | MEN1KMT2ASLC22A6SLC22A8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |