SCHEMBL1491848

SCHEMBL1491848

COc1cc(C(=O)CO)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
SLC22A6 Q4U2R8 1/20 0.68
SLC22A8 Q8TCC7 1/20 0.68
RAB9A P51151 1/20 0.68
HTT P42858 1/20 0.66
CYP1A2 P05177 1/20 0.64
HSP90AA1 P07900 1/20 0.64
HSP90AB1 P08238 1/20 0.64
BLM P54132 1/20 0.64
HSD17B2 P37059 1/20 0.61
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
NFKB1 P19838 2/20 0.57
ALOX5 P09917 1/20 0.57
STAT3 P40763 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57
GAA P10253 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL27438401 0.86 MEN1 (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL29595420 0.86 SLC22A6 (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL4545341 0.86 SLC22A6 (0.64) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL4716199 0.86 PDE4B (0.58) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL1396833 0.86 MEN1 (0.68) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL3893527 0.85 TSHR (0.66) MEN1KMT2ACYP1A2POLBHDAC6
Apocynin SCHEMBL9828393 0.85 SLC22A6 (0.54) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL7433907 0.84 MEN1 (0.66) MEN1KMT2ASLC22A6SLC22A8RAB9A
Water SCHEMBL27923532 0.84 PDE4B (0.57) MEN1KMT2ASLC22A6SLC22A8RAB9A
SCHEMBL16360980 0.84 MEN1 (0.66) MEN1KMT2ASLC22A6SLC22A8RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396463-A A kind of hill gooseberry's soak type fruit wine preparation process and optimization method UNIV MINNAN NORMAL 2019-11-01 CN claimed
CN-110044832-A The measuring method of general flavone content in a kind of semen litchi 广西中医药大学 2019-07-23 CN claimed
CN-104568930-B Method for determining content of catechuic acid in tea and tea products 昆明理工大学 2017-05-10 CN claimed
CN-104568930-A Method for determining content of catechuic acid in tea and tea products UNIV KUNMING SCIENCE & TECHNOLOGY 2015-04-29 CN claimed
WO-2013173332-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN Vertichem Corporation (CA) 2013-11-21 WO claimed
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN THESIS CHEMISTRY, LLC (US) 2013-09-12 US claimed
WO-2013134756-A1 A METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN Vertichem Corporation (CA) 2013-09-12 WO claimed
EP-2046147-B1 METHOD OF USING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2013-05-01 EP claimed
CN-102384907-B Method by utilize vanillin-sulfuric acid colorimetry to measure glabridin content UNIV HENAN SCIENCE & TECH 2013-04-03 CN claimed
CN-102478499-A Method for detecting oxidation resistance of larch bark extract XIUTING MA 2012-05-30 CN claimed
CN-102384907-A Method by utilize vanillin-sulfuric acid colorimetry to measure glabridin content UNIV HENAN SCIENCE & TECH 2012-03-21 CN claimed
CN-101865835-A Nitraria sibirica pall juice quality control method NORTHWEST INST PLATEAU BIO CAS 2010-10-20 CN claimed
CN-101865836-A Quality control method of Tibetan medicine lycium ruthenicum NORTHWEST INST PLATEAU BIO CAS 2010-10-20 CN claimed
CN-101858859-A Quality control method of lycium ruthenicum pigment NORTHWEST INST PLATEAU BIO CAS 2010-10-13 CN claimed
CN-101852729-A Quality control method of black fruit lyceum juice NORTHWEST INST PLATEAU BIO CAS 2010-10-06 CN claimed
US-20090311403-A1 Method of Using Organic Compounds GIVAUDAN SA (CH) 2009-12-17 US claimed
EP-4181781-B1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIV KINDERSPITAL BEIDER BASEL (CH) 2026-05-20 EP disclosed
US-5550130-A ANTIPSYCHOTIC AGENTS, ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1996-08-27 US disclosed
WO-1995011680-A1 HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1995-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090311403-A1 Method of Using Organic Compounds MGLL, GK, LIPC MEN1 1073/4885KMT2A 3062/4885SLC22A6 1279/4885
US-20130232852-A1 METHOD FOR TIERED PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM LIGNIN DCXR, AGL, GLO1 MEN1 4418/4885KMT2A 2781/4885SLC22A6 4361/4885
US-20130232853-A1 METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN HAAO, HAO2, HACL2 MEN1 4741/4885KMT2A 2677/4885SLC22A6 4438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.