Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22507577 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP8CTSBALOX15ELANE | |
| SCHEMBL26757664 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MMP8CTSBALOX15ELANE | |
| SCHEMBL3523749 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MMP8CTSBALOX15ELANE | |
| SCHEMBL1555297 | 0.89 | ALDH1A1 (0.57) | ALDH1A1MMP8CTSBMDM2MAPK1 | |
| SCHEMBL7298214 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MMP8CTSBMDM2MAPK1 | |
| SCHEMBL26758250 | 0.87 | ALDH1A1 (0.49) | ALDH1A1MMP8CTSBELANETACR1 | |
| SCHEMBL10708405 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MMP8CTSBALOX15ELANE | |
| SCHEMBL856250 | 0.86 | MMP8 (0.69) | ALDH1A1MMP8MDM2MAPK1L3MBTL1 | |
| SCHEMBL17156384 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MMP8CTSBALOX15MDM2 | |
| SCHEMBL10415038 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CTSBALOX15ELANEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |