Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | POLQ | O75417 | 5/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577293 | 0.84 | DRD4 (0.64) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL10282320 | 0.83 | DRD4 (0.67) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL654170 | 0.83 | DRD4 (0.63) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL12359040 | 0.83 | DRD4 (0.67) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL209154 | 0.82 | DRD4 (0.61) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL22502314 | 0.80 | ALDH1A1 (0.50) | DRD4 | |
| SCHEMBL19231633 | 0.79 | DRD4 (0.62) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL3455174 | 0.79 | DRD4 (0.59) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL10244827 | 0.79 | DRD4 (0.62) | DRD4POLQAURKACACNA2D1CACNA1B | |
| SCHEMBL7446241 | 0.79 | DRD4 (0.40) | DRD4POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |