Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929283 | 0.87 | SCN4A (0.43) | DRD4LMNAMEN1KMT2AMAPT | |
| SCHEMBL7440010 | 0.86 | OPRM1 (0.40) | MEN1KMT2AMAPTALDH1A1SCN4A | |
| SCHEMBL22407742 | 0.85 | HTT (0.44) | DRD4LMNAMEN1KMT2AMAPT | |
| SCHEMBL7288792 | 0.83 | ADRB1 (0.45) | DRD4LMNAMAPTALDH1A1SCN4A | |
| SCHEMBL7434249 | 0.79 | DRD4 (0.61) | DRD4POLQ | |
| SCHEMBL7440844 | 0.79 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11929144 | 0.78 | HTT (0.47) | LMNAMEN1KMT2AALDH1A1SCN4A | |
| SCHEMBL22502314 | 0.78 | ALDH1A1 (0.50) | DRD4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7435500 | 0.72 | ALDH1A1 (0.57) | DRD4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL22423693 | 0.71 | SCN4A (0.44) | LMNAMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |