Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428145 | 1.00 | CA12 (0.37) | CA12CA2CA1CA9TSHR | |
| SCHEMBL21271433 | 0.87 | TSHR (0.44) | CA12CA2CA1CA9TSHR | |
| SCHEMBL21271432 | 0.87 | TSHR (0.44) | CA12CA2CA1CA9TSHR | |
| SCHEMBL21271435 | 0.87 | TSHR (0.44) | CA12CA2CA1CA9TSHR | |
| SCHEMBL7433794 | 0.82 | CTSK (0.38) | CA12CA2CA1CA14CYP1A2 | |
| SCHEMBL7433793 | 0.82 | CTSK (0.38) | CA12CA2CA1CA14CYP1A2 | |
| SCHEMBL13407456 | 0.82 | CA12 (0.35) | CA12CA2CA14CYP1A2CYP2C9 | |
| SCHEMBL7442712 | 0.82 | CTSS (0.44) | TSHRCYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL7442709 | 0.82 | CTSS (0.44) | TSHRCYP2C9CYP2C19HTTL3MBTL1 | |
| SCHEMBL30841301 | 0.81 | MEN1 (0.47) | CA12CA2CA1CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |