Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788668 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL5753305 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL433287 | 0.81 | HDAC9 (0.50) | HDAC9 | |
| SCHEMBL5204567 | 0.80 | HDAC9 (0.40) | LMNAHDAC9 | |
| Trimethylammonium SCHEMBL27680853 | 0.79 | HDAC9 (0.45) | LMNAHDAC9 | |
| SCHEMBL1455575 | 0.78 | OPRM1 (0.45) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL30596332 | 0.78 | OPRM1 (0.45) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL12185878 | 0.77 | OPRM1 (0.44) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| Biphenyl SCHEMBL27506403 | 0.77 | HDAC9 (0.46) | HDAC9 | |
| SCHEMBL14214939 | 0.75 | OPRM1 (0.51) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |