Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27506403 | 0.94 | HDAC9 (0.46) | HDAC9HCAR2KDM1AMAOBAKR1C1 | |
| Trimethylammonium SCHEMBL27680853 | 0.93 | HDAC9 (0.45) | HDAC9HCAR2KDM1AMAOBAKR1C1 | |
| SCHEMBL687495 | 0.89 | AKR1C1 (0.48) | HDAC9HCAR2KDM1AAKR1C1TSHR | |
| SCHEMBL30219063 | 0.89 | AKR1C1 (0.48) | HDAC9HCAR2KDM1AAKR1C1TSHR | |
| SCHEMBL9735969 | 0.88 | HDAC9 (0.44) | HDAC9HCAR2KDM1AMAOBAKR1C1 | |
| SCHEMBL17335394 | 0.82 | KDM1A (0.46) | HDAC9HCAR2KDM1AMAOBTDP1 | |
| SCHEMBL5204567 | 0.81 | HDAC9 (0.40) | HDAC9HCAR2KDM1ATDP1 | |
| SCHEMBL7434294 | 0.81 | SMN1; SMN2 (0.48) | HDAC9 | |
| SCHEMBL6660381 | 0.80 | PARP10 (0.43) | HDAC9KDM1A | |
| SCHEMBL30638075 | 0.79 | THRB (0.42) | HDAC9HCAR2AKR1C1TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7032562-A | — | — | None | — | — | JP | disclosed |
| CN-110337357-A | The manufacturing method of thermoplastic resin membrane and thermoplastic resin membrane | 富士胶片株式会社 | 2019-10-15 | — | — | CN | disclosed |
| EP-3164266-B1 | MULTI-LAYER MATERIALS AND ARTICLES MADE THEREFROM AND METHODS OF MAKING | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-05-29 | — | — | EP | disclosed |
| US-10076888-B2 | Multi-layer materials and articles made therefrom and methods of making | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-09-18 | — | — | US | disclosed |
| CN-103351583-B | The polymer blend and its product for including cyclobutanediol with certain of logarithmic viscosity number and medium glass transition temperature combination | 伊士曼化工公司 | 2018-08-28 | — | — | CN | disclosed |
| CN-108424745-A | Active energy ray polymer resin composition, bonding agent, smears, laminated body and laminated body used for optical elements | 东洋油墨SC控股株式会社 | 2018-08-21 | — | — | CN | disclosed |
| EP-2333001-B1 | COMPOSITIONS OF POLYESTERS WITH A HIGH GLASS TRANSITION TEMPERATURE WHICH COMPRISE 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS AND ARTICLES THEREOF | EASTMAN CHEM CO (US) | 2018-07-25 | — | — | EP | disclosed |
| US-10017606-B2 | Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and moderate glass transition temperature and articles made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180117871-A1 | MULTI-LAYER MATERIALS AND ARTICLES MADE THEREFROM AND METHODS OF MAKING | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-05-03 | — | — | US | disclosed |
| CN-105358584-B | Active energy ray-polymerizable resin composition, adhesive, coating agent, laminate, and laminate for optical element | 东洋油墨SC控股株式会社 | 2018-04-27 | — | — | CN | disclosed |
| US-20070105993-A1 | Polyester compositions which comprise cyclobutanediol and at least one phosphorus compound | EASTMAN CHEMICAL COMPANY | 2007-05-10 | — | — | US | disclosed |
| WO-2007053549-A1 | POLYESTER COMPOSITIONS CONTAINING CYCLOBUTANEDIOL HAVING A CERTAIN COMBINATION OF INHERENT VISCOSITY AND MODERATE GLASS TRANSITION TEMPERATURE AND ARTICLES MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100125-A1 | Polyester compositions comprising minimal amounts of cyclobutanediol | EASTMAN CHEMICAL COMPANY | 2007-05-03 | — | — | US | disclosed |
| US-20070100122-A1 | Polyester compositions containing cyclobutanediol and articles made therefrom | EASTMAN CHEMICAL COMPANY | 2007-05-03 | — | — | US | disclosed |
| EP-1748984-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005110987-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050256164-A1 | NK1 and NK3 antagonists | PFIZER INC | 2005-11-17 | — | — | US | disclosed |
| US-5712377-A | COMPOUNDS FOR MODULATE THE IMMUNE SYSTEM, ANTITUMOR AGENTS AND VIRAL DISEASES | CERBIOS-PHARMA SA (CH) | 1998-01-27 | — | — | US | disclosed |
| JP-H0732562-A | EASILY ADHESIVE LAMINATED POLYESTER FILM | TEIJIN LTD | 1995-02-03 | — | — | JP | disclosed |
| JP-H00732562-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256164-A1 | NK1 and NK3 antagonists | TAC3, TACR1, TACR2 | HDAC9 1981/4885HCAR2 957/4885KDM1A 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.