Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474155 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL10588553 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL13332178 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1RECQLTAAR1MMP8 | |
| SCHEMBL10952521 | 0.78 | GGPS1 (0.41) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL2175542 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL28352359 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| Ammonia Solution, Strong SCHEMBL27747945 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL11592767 | 0.73 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL10483820 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG | |
| SCHEMBL9107668 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1AALDH1A1RECQLPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |