Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588553 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 | |
| SCHEMBL10952521 | 0.91 | GGPS1 (0.41) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 | |
| SCHEMBL7434331 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 | |
| SCHEMBL11592767 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 | |
| SCHEMBL31588359 | 0.83 | SLC13A5 (0.44) | SLC6A2CYP2D6CYP1A2 | |
| SCHEMBL9107668 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 | |
| SCHEMBL13332178 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2TAAR1ALDH1A1RECQLLMNA | |
| SCHEMBL11827986 | 0.74 | SLC13A5 (0.51) | SLC6A2PPARGPPARALMNA | |
| SCHEMBL28168069 | 0.73 | ALDH1A1 (0.67) | SMN1; SMN2HIF1AALDH1A1RECQLCYP3A4 | |
| SCHEMBL27908890 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2HIF1ASLC6A2TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583903-B | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115583903-A | Method for rapidly preparing racecadotril | 湖北广辰药业有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-108430968-A | Industrial process for the preparation of (5S,10S) -10-benzyl-16-methyl-11, 14, 18-trioxo-15, 17, 19-trioxa-2, 7, 8-trithia-12-azaheneicosane-5-ammonium (E) -3-carboxy acrylate | 领先药物公司 | 2018-08-21 | — | — | CN | disclosed |
| US-5208255-A | Enzyme inhibitors and treatment of cardiovascular disorders | SOCIETE CIVILE BIOPROJET (FR) | 1993-05-04 | — | — | US | disclosed |
| CN-1033803-A | The preparation of hypotensive agent mercapto-acylamino acid | SCHERING CORP (US) | 1989-07-12 | — | — | CN | disclosed |
| EP-0322633-A1 | Mercapto-acylamino acid antihypertensives | SCHERING CORPORATION (US) | 1989-07-05 | — | — | EP | disclosed |