Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 9/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 9/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 9/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434516 | 1.00 | ELANE (0.47) | ELANETPSAB1TPSD1TPSG1PLAU | |
| Hydrochloric Acid SCHEMBL7349290 | 0.99 | ELANE (0.46) | ELANETPSAB1TPSD1TPSG1PLAU | |
| Hydrochloric Acid SCHEMBL7349279 | 0.99 | ELANE (0.46) | ELANETPSAB1TPSD1TPSG1PLAU | |
| SCHEMBL7443391 | 0.87 | ELANE (0.49) | ELANETPSAB1TPSD1TPSG1PLAU | |
| Hydrochloric Acid SCHEMBL7320686 | 0.86 | ELANE (0.48) | ELANETPSAB1TPSD1TPSG1PLAU | |
| SCHEMBL7432344 | 0.82 | ELANE (0.47) | ELANETPSAB1TPSD1TPSG1PLAU | |
| Hydrochloric Acid SCHEMBL7320024 | 0.81 | ELANE (0.46) | ELANETPSAB1TPSD1TPSG1PLAU | |
| SCHEMBL7320639 | 0.81 | ALOX15 (0.33) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL7320645 | 0.81 | ALOX15 (0.33) | TPSAB1TPSD1TPSG1 | |
| Hydrochloric Acid SCHEMBL7355532 | 0.81 | TPSAB1 (0.54) | ELANETPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037819-A | Anticoagulant; treating pancreatitis | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-08-06 | — | — | US | claimed |