Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433262 | 0.85 | RAB9A (0.43) | ALDH1A1HSD17B10USP2RAB9ASMN1; SMN2 | |
| SCHEMBL7430635 | 0.81 | CASR (0.46) | ALDH1A1HSD17B10USP2RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7430574 | 0.79 | RAB9A (0.55) | ALDH1A1HSD17B10USP2RAB9AMAPT | |
| SCHEMBL7434594 | 0.79 | RAB9A (0.47) | ALDH1A1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL5077522 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HSD17B10RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7438956 | 0.78 | CASR (0.50) | ALDH1A1HSD17B10USP2RAB9ASMN1; SMN2 | |
| SCHEMBL7428258 | 0.77 | RAB9A (0.53) | ALDH1A1RAB9AMAPTHTTLMNA | |
| SCHEMBL7435427 | 0.77 | NPSR1 (0.52) | ALDH1A1HSD17B10USP2MAPTCASR | |
| SCHEMBL17540324 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD17B10USP2RAB9ASMN1; SMN2 | |
| SCHEMBL7434607 | 0.76 | ALDH1A1 (0.52) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |