Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936757 | 0.82 | MAOB (0.56) | MAOBMAOAPTPN1FTOKDM4E | |
| SCHEMBL28572449 | 0.76 | CHRM2 (0.41) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL2490828 | 0.74 | CHRM2 (0.50) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL9387217 | 0.72 | MIF (0.53) | MAOBMAOAPTPN1KDM4EALDH1A1 | |
| SCHEMBL24682836 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL1311305 | 0.70 | NQO1 (0.48) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL12183 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL22955630 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL12842832 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 | |
| SCHEMBL8769445 | 0.70 | MAOB (0.44) | MAOBMAOAPTPN1FTOCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582978-A | 3-thio-benzofuran derivative and synthesis method thereof | 齐鲁工业大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113651838-B | Compound containing multiple boron-oxygen family atom hybrid fused ring units and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2023-03-24 | — | — | CN | disclosed |
| US-20230019060-A1 | HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | US | disclosed |
| CN-114539301-A | Dendritic fused ring compound containing boron atom and oxygen atom, preparation method and application thereof, and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2022-05-27 | — | — | CN | disclosed |
| CN-113651838-A | Compound containing multiple boron-oxygen family atom hybrid fused ring units and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2021-11-16 | — | — | CN | disclosed |
| CN-113582978-A | 3-thio-benzofuran derivative and synthesis method thereof | 齐鲁工业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113582978-A | 3-thio-benzofuran derivative and synthesis method thereof | 齐鲁工业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113582978-A | 3-thio-benzofuran derivative and synthesis method thereof | 齐鲁工业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-112851700-A | Condensed ring compound containing boron atom, oxygen atom and five-membered aromatic heterocycle and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2021-05-28 | — | — | CN | disclosed |
| US-10544183-B2 | Uridine nucleoside derivatives, compositions and methods of use | TUFTS UNIVERSITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-8546607-B2 | Cross-coupling of phenolic derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-01 | — | — | US | disclosed |
| US-7179586-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |
| US-5760048-A | TREATMENT OF STROKE AND NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5554767-A | NERVOUS SYSTEM, CARDIOVASCULAR, AND BRAIN DISORDERS | WARNER-LAMBERT COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019060-A1 | HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT | CRBN, MDM2, RBX1 | MAOB 2399/4885MAOA 2701/4885PTPN1 3411/4885 |
| US-10544183-B2 | Uridine nucleoside derivatives, compositions and methods of use | P2RY6, UPP1, UMPS | MAOB 2297/4885MAOA 2557/4885PTPN1 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.