SCHEMBL12183

SCHEMBL12183

Cc1coc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.44
MAOA P21397 4/20 0.44
PTPN1 P18031 1/20 0.44
CYP1A2 P05177 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
CA2 P00918 1/20 0.42
FTO Q9C0B1 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLC6A4 P31645 2/20 0.40
DRD2 P14416 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KCNA3 P22001 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28592905 0.98 MAOB (0.46) MAOBMAOAPTPN1CYP1A2CHRNB2
Formic Acid SCHEMBL28395993 0.88 MAOB (0.49) MAOBMAOAPTPN1CA2
Methylchromone SCHEMBL29387804 0.82 MAOB (0.56) MAOBMAOAPTPN1SMN1; SMN2
Methylchromone SCHEMBL25934 0.82 MAOB (0.56) MAOBMAOAPTPN1SMN1; SMN2
Methylchromone SCHEMBL29160528 0.81 MAOB (0.55) MAOBMAOAPTPN1SMN1; SMN2
Ethoxycarbonyl Group SCHEMBL29184215 0.79 MAOB (0.47) MAOBMAOAPTPN1CA2SMN1; SMN2
Methylchromone SCHEMBL3456497 0.75 MAOB (0.49) MAOBMAOAPTPN1SMN1; SMN2
SCHEMBL1133152 0.74 CHRM2 (0.41) MAOBMAOAPTPN1CYP1A2CHRNB2
SCHEMBL2490828 0.74 CHRM2 (0.50) MAOBMAOAPTPN1CA2FTO
SCHEMBL23919117 0.73 KCNA3 (0.46) MAOACYP1A2KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473283-B2 Compounds and their use DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-11-18 US claimed
WO-2025109563-A1 SPIRO-HYDANTOIN DERIVATIVE EXHIBITING ADAMTS-4 INHIBITORY ACTIVITY, AND USE THEREOF 서울대학교병원 2025-05-30 WO claimed
CN-119684263-A Synthetic method of terpetinib and key intermediate thereof 苏州莱安医药化学技术有限公司 2025-03-25 CN claimed
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US claimed
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-14 US claimed
US-20240317708-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-09-26 US claimed
US-11084771-B2 Method for purifying phenol LG CHEM, LTD. (KR) 2021-08-10 US claimed
CN-108633275-B Process for purifying phenol 株式会社LG化学 2021-07-27 CN claimed
US-20210198170-A1 METHOD FOR PURIFYING PHENOL LG CHEM, LTD. (KR) 2021-07-01 US claimed
CN-107188846-B A kind of synthetic method of arylseleno heterocyclic compound 温州医科大学 2019-08-20 CN claimed
EP-1153022-A1 PROTHEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2001-11-14 EP claimed
WO-2000049011-A1 PROTHEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-08-24 WO claimed
EP-1027344-A2 PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA PROTEOME SCIENCES PLC (GB) 2000-08-16 EP claimed
WO-1999006388-A2 PHARMACEUTICAL COMPOUNDS ISOLATED FROM ARISTOLOCHIA TALISCANA PROTEOME SCIENCES PLC. (GB) 1999-02-11 WO claimed
US-5459131-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1995-10-17 US claimed
US-5104869-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1992-04-14 US claimed
EP-0427939-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP claimed
EP-0147044-B1 BENZOFURANCARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM ADRIA LABORATORIES INC. (US) 1990-04-25 EP claimed
US-4888353-A Carboxamides useful as antiemetic or antipsychotic agents ERBAMONT, INC. (US) 1989-12-19 US claimed
EP-0147044-A2 Benzofurancarboxamides, process for their preparation and pharmaceutical preparations containing them ADRIA LABORATORIES INC. (US) 1985-07-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 MAOB 517/4885MAOA 527/4885PTPN1 4269/4885
US-20240376055-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 MAOB 517/4885MAOA 527/4885PTPN1 4269/4885
US-11084771-B2 Method for purifying phenol HACL2, GNPAT, ACACB MAOB 325/4885MAOA 321/4885PTPN1 2636/4885
US-20240317708-A1 INHIBITORS OF TRANSGLUTAMINASES TGM2, TGM3, TGM1 MAOB 517/4885MAOA 527/4885PTPN1 4269/4885
US-12473283-B2 Compounds and their use LSS, PGLS, LDHB MAOB 917/4885MAOA 2023/4885PTPN1 2140/4885
US-20210198170-A1 METHOD FOR PURIFYING PHENOL HACL2, ACACB, MBOAT4 MAOB 475/4885MAOA 536/4885PTPN1 2872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.