Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434787 | 0.83 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5599612 | 0.75 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL5600230 | 0.73 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL7438143 | 0.73 | CRHR1 (0.42) | CRHR1NPY1R | |
| SCHEMBL7438135 | 0.71 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL20723106 | 0.71 | CRHR1 (0.43) | CRHR1TSHR | |
| SCHEMBL5600236 | 0.69 | CRHR1 (0.42) | CRHR1NPY1R | |
| SCHEMBL20722854 | 0.69 | CRHR1 (0.41) | CRHR1TSHR | |
| SCHEMBL27670940 | 0.67 | CYP1A2 (0.43) | CRHR1NPY1R | |
| SCHEMBL13134057 | 0.67 | CRHR1 (0.70) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |