Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL17728304 | 0.89 | SLC7A5 (0.38) | SLC7A5ITGB3ITGA2BLNPEPOPRM1 | |
| Proline SCHEMBL17728309 | 0.87 | SLC7A5 (0.40) | SLC7A5ITGB3ITGA2BLNPEPOPRM1 | |
| Tyrosine SCHEMBL9686139 | 0.87 | SLC7A5 (0.50) | SLC7A5 | |
| Tyrosine SCHEMBL15264616 | 0.87 | SLC7A5 (0.50) | SLC7A5ITGB3ITGA2BLNPEPOPRM1 | |
| Tyrosine SCHEMBL7434891 | 0.87 | SLC7A5 (0.50) | SLC7A5ITGB3ITGA2BLNPEPOPRM1 | |
| Tyrosine SCHEMBL4352798 | 0.87 | SLC7A5 (0.57) | SLC7A5OPRM1MAPTITGA4DPP4 | |
| SCHEMBL4205064 | 0.86 | SLC7A5 (0.44) | SLC7A5ITGA4DPP4 | |
| Tyrosine SCHEMBL6064435 | 0.86 | SLC7A5 (0.46) | SLC7A5OPRM1GSRITGA4DPP4 | |
| Tyrosine SCHEMBL2205275 | 0.85 | SLC7A5 (0.47) | SLC7A5ITGA4DPP4NTSR2 | |
| SCHEMBL17728303 | 0.84 | SLC7A5 (0.46) | SLC7A5ITGA4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980753-A | Compositions and methods for improving and maintaining glucose metabolism in children and adolescents | 雀巢产品有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114423304-A | Compositions and methods for improvement and maintenance of weight loss | 雀巢产品有限公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-1144446-A1 | PHARMACEUTICAL COMPOUNDS FOR THE INHIBITION OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000031129-A1 | PHARMACEUTICAL COMPOUNDS FOR THE INHIBITION OF HEPATITIS C VIRUS NS3 PROTEASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2000-06-02 | — | — | WO | disclosed |