Tyrosine

Tyrosine

SCHEMBL4352798

N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(OC(=O)[C@@H]1CCCN1)[C@@H]1CCCN1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.57
PTGS1 P23219 3/20 0.42
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
XIAP P98170 1/20 0.42
DPP4 P27487 2/20 0.41
PCNA P12004 1/20 0.41
ALOX15 P16050 3/20 0.41
HIF1A Q16665 3/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
USP2 O75604 1/20 0.41
EGFR P00533 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
HTR2A P28223 1/20 0.41
PTGS2 P35354 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL9686139 0.91 SLC7A5 (0.50) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL4205064 0.89 SLC7A5 (0.44) SLC7A5DPP4CTSCITGA4HTR2C
Tyrosine SCHEMBL4205059 0.89 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL5152642 0.89 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL4205061 0.89 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL4352800 0.89 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL2205275 0.89 SLC7A5 (0.47) SLC7A5DPP4PCNACTSCITGA4
SCHEMBL17728303 0.88 SLC7A5 (0.46) SLC7A5DPP4PCNACTSCITGA4
Tyrosine SCHEMBL6064435 0.88 SLC7A5 (0.46) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL7434889 0.87 SLC7A5 (0.45) SLC7A5DPP4ITGA4OPRM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240093218-A1 NUCLEIC ACID CONSTRUCTS, PLANTS WITH INCREASED TUBER YIELD, AND METHODS FOR INCREASING TUBER YIELD IN A PLANT NATIONAL SCIENCE FOUNDATION 2024-03-21 US disclosed
US-11795468-B2 Nucleic acid constructs, plants with increased tuber yield, and methods for increasing tuber yield in a plant IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-10-24 US disclosed
US-20190218565-A1 NUCLEIC ACID CONSTRUCTS, PLANTS WITH INCREASED TUBER YIELD, AND METHODS FOR INCREASING TUBER YIELD IN A PLANT NATIONAL SCIENCE FOUNDATION 2019-07-18 US disclosed
US-7579150-B1 screening a biomolecule such as protein, polypeptide, or ribonucleoprotein, for its ability to assist in mediating long-distance movement of a mobile RNA through phloem tissue of a plant; for enhancing growth in a plant IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2009-08-25 US disclosed
US-20080184396-A1 POTATO TRANSCRIPTION FACTORS, METHODS OF USE THEREOF, AND A METHOD FOR ENHANCING TUBER DEVELOPMENT IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2008-07-31 US disclosed
US-7265263-B1 Potato transcription factors, methods of use thereof, and a method for enhancing tuber development IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-09-04 US disclosed