Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PCNA | P12004 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL9686139 | 0.90 | SLC7A5 (0.50) | SLC7A5TYRCTSCPTGS1ALPI | |
| SCHEMBL4205064 | 0.89 | SLC7A5 (0.44) | SLC7A5ITGA4DPP4TYRCTSC | |
| Tyrosine SCHEMBL20575032 | 0.88 | SLC7A5 (0.52) | SLC7A5KDM4ENAALAD2ITGA4DPP4 | |
| Tyrosine SCHEMBL4352798 | 0.88 | SLC7A5 (0.57) | SLC7A5KDM4EITGA4DPP4PCNA | |
| SCHEMBL17728303 | 0.87 | SLC7A5 (0.46) | SLC7A5ITGA4DPP4TYRPCNA | |
| Tyrosine SCHEMBL7434889 | 0.86 | SLC7A5 (0.45) | SLC7A5ITGA4DPP4GSROPRM1 | |
| Tyrosine SCHEMBL2205275 | 0.85 | SLC7A5 (0.47) | SLC7A5ITGA4DPP4TYRPCNA | |
| Cystine SCHEMBL7594899 | 0.83 | SLC7A5 (0.46) | SLC7A5KDM4ENAALAD2ITGA4DPP4 | |
| SCHEMBL498386 | 0.81 | CTSC (0.50) | SLC7A5DPP4TYRCTSCCYP1A2 | |
| SCHEMBL3726266 | 0.81 | CTSC (0.50) | SLC7A5DPP4TYRCTSCCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018654-B2 | Pharmaceutical composition containing an active agent in an amino acid copolymer structure | NEW RIVER PHARMACEUTICALS INC. (US) | 2006-03-28 | — | — | US | disclosed |
| US-20020128177-A1 | Use of protein conformation for the protection and release of chemical compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2002-09-12 | — | — | US | disclosed |