Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439861 | 1.00 | ACE (0.54) | ACE | |
| SCHEMBL5175052 | 0.85 | ACE (0.63) | ACE | |
| Hydrochloric Acid SCHEMBL7439988 | 0.84 | ACE (0.70) | ACE | |
| SCHEMBL11049962 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL11049974 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL11035895 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL11050522 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL11050512 | 0.82 | ACE (0.73) | ACE | |
| SCHEMBL7433990 | 0.81 | ACE (0.66) | ACE | |
| Hydrochloric Acid SCHEMBL7430196 | 0.80 | ACE (0.65) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104546-A2 | Therapeutic dipeptides | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-04 | — | — | EP | claimed |
| US-4500713-A | TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AS ANTIHYPERTENSIVE AGENT | USV PHARMACEUTICAL CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0104546-A2 | Therapeutic dipeptides | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-04 | — | — | EP | disclosed |