Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035895 | 0.93 | ACE (0.73) | ACEABCB11 | |
| SCHEMBL11049974 | 0.93 | ACE (0.73) | ACEABCB11 | |
| SCHEMBL11050512 | 0.93 | ACE (0.73) | ACEABCB11 | |
| SCHEMBL11050522 | 0.93 | ACE (0.73) | ACEABCB11 | |
| SCHEMBL11049962 | 0.93 | ACE (0.73) | ACEABCB11 | |
| SCHEMBL7439861 | 0.85 | ACE (0.54) | ACE | |
| SCHEMBL7434890 | 0.85 | ACE (0.54) | ACE | |
| SCHEMBL11187981 | 0.84 | ACE (0.67) | ACEABCB11 | |
| SCHEMBL8280065 | 0.84 | ACE (0.67) | ACEABCB11 | |
| Perindopril SCHEMBL7374714 | 0.82 | ACE (0.66) | ACEABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208607-B1 | Process for synthesis of perindopril and pharmaceutically acceptable salts thereof | LES LABORATOIRES SERVIER (FR) | 2007-04-24 | — | — | US | disclosed |
| US-20070083052-A1 | PROCESS FOR SYNTHESIS OF PERINDOPRIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF. | LES LABORATOIRES SERVIER (FR) | 2007-04-12 | — | — | US | disclosed |
| EP-1420028-B1 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | SERVIER LAB (FR) | 2007-02-21 | — | — | EP | disclosed |
| EP-1420028-A2 | Method for synthesis of perindopril and its pharmaceutically acceptable salts | LES LABORATOIRES SERVIER (FR) | 2004-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070083052-A1 | PROCESS FOR SYNTHESIS OF PERINDOPRIL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF. | ACE, REN, QDPR | ACE 1/4885ABCB11 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.