Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.88 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.88 |
| ▸ | MEN1 | O00255 | 1/20 | 0.88 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.88 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 11/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425481 | 1.00 | PDE4A (0.88) | PDE4APDE4DMEN1CHRM1KMT2A | |
| SCHEMBL5426026 | 1.00 | PDE4A (0.88) | PDE4APDE4DMEN1CHRM1KMT2A | |
| SCHEMBL5424919 | 1.00 | PDE4A (0.88) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Levotofisopam SCHEMBL5431173 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Tofisopam SCHEMBL4585183 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Dextofisopam SCHEMBL29376877 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Tofisopam SCHEMBL43522 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Tofisopam SCHEMBL8086894 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Tofisopam SCHEMBL29832594 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A | |
| Dextofisopam SCHEMBL236796 | 0.94 | KMT2A (1.00) | PDE4APDE4DMEN1CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |