Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422784 | 0.71 | AURKA (0.35) | AURKAKDM4EL3MBTL1RPS6KB1ALDH1A1 | |
| SCHEMBL7435199 | 0.65 | KDM4E (0.34) | PARP1AURKAKDM4EL3MBTL1RPS6KB1 | |
| SCHEMBL16116287 | 0.63 | PARP1 (0.46) | PARP1AURKAKDM4EPARP2ALDH1A1 | |
| SCHEMBL29354955 | 0.63 | PARP1 (0.46) | PARP1AURKAKDM4EPARP2ALDH1A1 | |
| SCHEMBL21296626 | 0.63 | NPC1 (0.32) | KDM4EALDH1A1KMT2AMEN1ALOX15 | |
| SCHEMBL7268507 | 0.63 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1HTTLMNA | |
| SCHEMBL6837959 | 0.62 | MEN1 (0.40) | PARP1AURKAKDM4EL3MBTL1PARP2 | |
| SCHEMBL31023195 | 0.62 | ALDH1A1 (0.44) | PARP1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL6727096 | 0.62 | MEN1 (0.37) | PARP1KDM4EL3MBTL1ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL20510158 | 0.62 | PARP1 (0.45) | PARP1AURKAKDM4EPARP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403261-A2 | Amide derivatives | GLAXO GROUP LIMITED (GB) | 1990-12-19 | — | — | EP | disclosed |