Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299850 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MMP1MMP2MMP3MMP9 | |
| SCHEMBL11350460 | 0.89 | HCAR2 (0.42) | SMN1; SMN2HCAR2KEAP1NFE2L2EPHX1 | |
| SCHEMBL1143801 | 0.88 | ACHE (0.46) | MMP2EPHX1BCHECNR1 | |
| SCHEMBL1143798 | 0.88 | ACHE (0.46) | MMP2EPHX1BCHECNR1 | |
| SCHEMBL19204393 | 0.86 | EPHX1 (0.53) | EPHX1PAOX | |
| SCHEMBL17845062 | 0.85 | EPHX1 (0.56) | EPHX1 | |
| SCHEMBL1972526 | 0.84 | NPSR1 (0.47) | MMP1MMP2MMP3MMP9HCAR2 | |
| SCHEMBL1972523 | 0.84 | NPSR1 (0.47) | MMP1MMP2MMP3MMP9HCAR2 | |
| SCHEMBL1972528 | 0.84 | NPSR1 (0.47) | MMP1MMP2MMP3MMP9HCAR2 | |
| SCHEMBL17858890 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | claimed |
| US-5342847-A | Antiischetic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| EP-0551663-A1 | Dimethyl 2,6-dimethyl-1n-propyl-4-(4-trifluormethylphenyl)-1,4-dihydro-pyridine-3,5-dicarboxylate, method for its production and its pharmaceutical use | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| US-RE32975-E | FUNGICIDES, BACTERICIDES, FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0004279-B1 | PROCESS FOR THE PREPARATION OF 4-PYRIDONE-3-CARBOXYLIC ACIDS, 1-CYCLOPROPYL-4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES AND MEDICINES CONTAINING THEM | BAYER AG (DE) | 1982-12-29 | — | — | EP | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |