Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350460 | 0.89 | HCAR2 (0.42) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL11571418 | 0.83 | KDM4E (0.48) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL7435242 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL9299850 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL28792616 | 0.82 | NPSR1 (0.46) | HCAR2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11738393 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL11738371 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR | |
| SCHEMBL29308972 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AUSP2MAPT | |
| SCHEMBL28792604 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AUSP2MAPT | |
| SCHEMBL20928885 | 0.80 | DNM1 (0.40) | SMN1; SMN2HCAR2KEAP1NFE2L2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) | 2017-11-16 | — | — | US | disclosed |
| WO-2016097169-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | UNIVERSITEIT GENT (BE) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327625-A1 | COMPOSITIONS COMPRISING A POLYMERIC NETWORK | CHRNA5, CHRNA1, CHRM1 | SMN1; SMN2 1218/4885HCAR2 1259/4885KEAP1 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.