Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857448 | 0.85 | ESR1 (0.38) | HTTTRPA1 | |
| SCHEMBL18700118 | 0.77 | TYR (0.46) | IDO1HTTTRPA1ALDH1A1GAA | |
| SCHEMBL84956 | 0.77 | IDO1 (0.46) | IDO1TDO2ACHEAOC3DAO | |
| SCHEMBL7893366 | 0.77 | ESR1 (0.52) | IDO1TDO2ACHEAOC3DAO | |
| SCHEMBL12027408 | 0.77 | IDO1 (0.46) | IDO1TDO2ACHEAOC3DAO | |
| SCHEMBL24838557 | 0.77 | TYR (0.46) | IDO1HTTTRPA1ALDH1A1GAA | |
| SCHEMBL21840890 | 0.74 | IDO1 (0.44) | IDO1TDO2ACHEAOC3DAO | |
| SCHEMBL24127908 | 0.74 | ACHE (0.47) | ACHEMAOAMAOBALDH1A1GAA | |
| Ammonia Solution, Strong SCHEMBL7995946 | 0.74 | ESR1 (0.50) | IDO1TDO2ACHEAOC3DAO | |
| SCHEMBL7434382 | 0.74 | ACHE (0.47) | ACHEMAOAMAOBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219453-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-20180155279-A1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS, INC. | 2018-06-07 | — | — | US | disclosed |
| US-20110257163-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION | 2011-10-20 | — | — | US | disclosed |
| US-20110257163-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION | 2011-10-20 | — | — | US | disclosed |
| WO-2009020579-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| CN-1119014-A | Benzopyranes as potassium channel openers | PFIZER LTD (GB) | 1996-03-20 | — | — | CN | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155279-A1 | ARYL ETHERS AND USES THEREOF | HIF1AN, EGLN2, VHL | IDO1 1555/4885TDO2 539/4885ACHE 4882/4885 |
| US-20110257163-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, PSEN1 | IDO1 4454/4885TDO2 4772/4885ACHE 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.