Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440554 | 0.87 | MEN1 (0.65) | MEN1KMT2ACYP19A1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7428326 | 0.86 | MEN1 (0.67) | MEN1KMT2ACYP19A1CHRM2CHRM1 | |
| SCHEMBL9782821 | 0.84 | CHRM2 (0.47) | MEN1KMT2ACHRM2CHRM1CYP2D6 | |
| SCHEMBL7436761 | 0.84 | TSHR (0.54) | MEN1KMT2ACYP19A1CHRM2CHRM1 | |
| SCHEMBL7442966 | 0.84 | CHRM2 (0.63) | CHRM2CHRM1CYP2D6KCNH2TP53 | |
| Hydrochloric Acid SCHEMBL7444697 | 0.83 | TSHR (0.53) | MEN1KMT2ACYP19A1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7433381 | 0.83 | TP53 (0.48) | MEN1KMT2ACHRM2CHRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7436495 | 0.83 | TP53 (0.63) | MEN1KMT2ACHRM2CHRM1CYP2D6 | |
| SCHEMBL7434962 | 0.80 | ALDH1A1 (0.57) | MEN1KMT2ACYP19A1ALDH1A1 | |
| Bromide SCHEMBL7445477 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037848-A | Aryl-cycloalkyl-alkanolamines for treatment of epilepsy | WASHINGTON UNIVERSITY (US) | 1991-08-06 | — | — | US | disclosed |
| US-4988710-A | Anticonvulsants, anticholinergic agents, aryl-cycloalkanolamines | WASHINGTON UNIVERSITY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4945097-A | THERAPY FOR ANOXIA, HYPOXIA, OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-07-31 | — | — | US | disclosed |