Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429609 | 0.88 | POLB (0.40) | LMNAPOLB | |
| SCHEMBL1838256 | 0.86 | ACLY (0.50) | ACLYPTGES2POLBKDM4CTRPV4 | |
| SCHEMBL6239161 | 0.82 | PTGES2 (0.46) | ACLYPTGES2LMNAPOLBKDM4C | |
| SCHEMBL20761848 | 0.76 | HTT (0.46) | ACLYPTGES2ALDH1A1LMNATRPV4 | |
| SCHEMBL1836125 | 0.76 | FFAR4 (0.57) | ACLYPTGES2POLBKDM4CFFAR4 | |
| SCHEMBL29825398 | 0.76 | PDCD1 (0.50) | PTGES2ALDH1A1LMNAPOLBKDM4C | |
| SCHEMBL1679612 | 0.76 | PDCD1 (0.50) | PTGES2ALDH1A1LMNAPOLBKDM4C | |
| SCHEMBL16791808 | 0.75 | POLB (0.43) | ACLYLMNAPOLBTRPV4 | |
| SCHEMBL7486627 | 0.75 | KDM4E (0.39) | ALDH1A1POLB | |
| SCHEMBL13743842 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |