Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436298 | 0.89 | HTR1A (0.66) | HTR1ASLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL7434915 | 0.89 | HTR1A (0.71) | HTR1ASLC6A4HRH3 | |
| SCHEMBL7444890 | 0.88 | HTR1A (0.57) | HTR1ASLC6A4HRH3CCR2LTA4H | |
| SCHEMBL7444624 | 0.82 | HRH3 (0.55) | HTR1ASLC6A4HRH3CCR2LTA4H | |
| SCHEMBL7434240 | 0.81 | SLC6A4 (0.61) | HTR1ASLC6A4HRH3LTA4HSLC6A2 | |
| Hydrochloric Acid SCHEMBL6601400 | 0.81 | HTR1A (0.98) | HTR1A | |
| SCHEMBL7427779 | 0.81 | SLC7A5 (0.61) | HTR1ASLC6A4HRH3LTA4HSLC6A2 | |
| SCHEMBL7435052 | 0.79 | HRH3 (0.62) | HTR1ASLC6A4HRH3LTA4H | |
| Oxalic Acid SCHEMBL4739539 | 0.78 | HTR1A (0.66) | HTR1ASLC6A4HRH3CCR2 | |
| SCHEMBL7430403 | 0.78 | SLC6A4 (0.57) | HTR1ASLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |