Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.61 |
| ▸ | HTR1A | P08908 | 11/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7437107 | 0.94 | SLC6A4 (0.56) | SLC6A4HRH3HTR1ASLC6A2SLC6A3 | |
| SCHEMBL7435052 | 0.85 | HRH3 (0.62) | SLC6A4HRH3HTR1ALTA4H | |
| SCHEMBL7430403 | 0.84 | SLC6A4 (0.57) | SLC6A4HRH3HTR1ASLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL4739539 | 0.84 | HTR1A (0.66) | SLC6A4HRH3HTR1A | |
| Oxalic Acid SCHEMBL4739725 | 0.83 | HTR1A (0.67) | SLC6A4HRH3HTR1ASLC6A2SLC6A3 | |
| SCHEMBL7435355 | 0.82 | HRH3 (0.57) | SLC6A4HRH3HTR1AKCNH2 | |
| SCHEMBL7435335 | 0.81 | HTR1A (0.68) | SLC6A4HRH3HTR1ASLC6A2SLC6A3 | |
| SCHEMBL17267470 | 0.80 | SLC7A5 (0.65) | SLC6A4HRH3HTR1ASLC6A2SLC6A3 | |
| SCHEMBL4734353 | 0.79 | SLC6A4 (0.76) | SLC6A4HRH3SLC6A2SLC6A3LTA4H | |
| SCHEMBL8722851 | 0.79 | HRH3 (0.49) | SLC6A4HRH3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576766-A1 | Propanolamine derivatives, their preparation and use | NOVO NORDISK A/S (DK) | 1994-01-05 | — | — | EP | claimed |