Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435376 | 1.00 | CTSK (0.52) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL7435374 | 1.00 | CTSK (0.52) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL9556266 | 1.00 | CTSK (0.52) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL16480228 | 0.88 | CTSK (0.49) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL10545929 | 0.88 | CTSK (0.49) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL8034346 | 0.88 | CTSK (0.49) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL10549997 | 0.87 | CTSK (0.48) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL2192482 | 0.85 | CTSK (0.49) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL1922636 | 0.85 | CTSK (0.47) | CTSKCTSLCTSBCTSSCA1 | |
| SCHEMBL10420922 | 0.85 | CTSK (0.47) | CTSKCTSLCTSBCTSSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587767-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1994-03-23 | — | — | EP | disclosed |
| US-5268361-A | Containing amide groups | SRI INTERNATIONAL (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1992021696-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1992-12-10 | — | — | WO | disclosed |